Microbial Fermentation CMO Market Size Worth over USD 9.1 Billion in 2035 | Roots Analysis

Several factors contribute to the growth of the microbial fermentation market. The advantages offered by microbial expression systems over other systems, such as cost-effectiveness, high productivity, and the ability to genetically engineer microbes to produce a wide range of pharmaceutical compounds, including antibodies, proteins, peptides, and small molecules are among the most important growth drivers of the microbial fermentation CMO market.

Further, microbial fermentation can achieve higher productivity and yields compared to alternative expression platforms. Additionally, a shift has been observed in the biopharmaceutical pipeline towards more diverse biopharmaceuticals, and microbial fermentation is well-suited for producing such biologics, including nanobodies, DARPins, and single-chain antibodies. Advancements in microbial engineering, including improvements in genetic engineering, metabolic engineering, and fermentation process development, have further enhanced the capabilities of these systems.

Finally, the increased rate of outsourcing microbial fermentation processes to specialized contract development and manufacturing organizations (CDMOs) has contributed to the rise in the use of microbial fermentation in the pharmaceutical industry, as companies leverage the expertise and infrastructure of these specialized providers. 

The microbial fermentation CMO market is anticipated to be worth USD 3.6 billion in 2024, and this value is likely to reach over USD 9.1 billion by 2035, expanding to a CAGR of 8.7% according to a new report by Roots Analysis.

Key Report Takeaways

§  Presently, more than 120 players are engaged in offering microbial fermentation contract manufacturing services across the globe; most of these players are headquartered in Europe

§  The current market landscape of microbial fermentation CMOs is fragmented, featuring the presence of both new entrants and established players; majority of these players offer process development services

§  Owing to the rise in demand for biologics, service providers and drug innovators are upgrading their technical expertise to efficiently manufacture high quality products using microbial expression systems

§  A comprehensive set of company profiles of prominent / emerging players offers valuable insights into their current strategic focus and future initiatives, empowering stakeholders with crucial information

§  The growing interest in this domain is evident from the rise in partnership activity; in fact, the maximum number of collaborations related to microbial fermentation were inked in the last two years

§  Industry players are making extensive efforts to expand their existing capacities and capabilities for both clinical and commercial microbial fermentation

§  Driven by the increasing pace of innovation and partnership activity, the market for microbial fermentation contract manufacturing is poised to witness steady growth in foreseeable future

§  The microbial fermentation CMO market is likely to grow at a CAGR of 8.7%, till 2035; presently, majority of the market share is occupied by an upstream bacterial expression system

§  The microbial fermentation contract manufacturing market is anticipated to be primarily driven by the rising demand for biologics; Europe is expected to capture a larger share (over 40%) of the market by 2035

Competitive Landscape of Microbial CMO

The current market landscape features the presence of over 120 contract service providers offering various services related to microbial fermentation; these include microbial strain development, microbial cell banking, analytical validation, process development, scale-up, downstream processing, aseptic fill finish manufacturing, regulatory support.

Further, the microbial fermentation CMO market features the presence of small, mid-sized, large and very large companies having the required expertise to offer contract manufacturing services across the globe. In addition, they have undertaken several initiatives, such as entering into partnerships, and expanding their existing capabilities and capacities, in order to cater to the increasing demand for biologics manufactured via microbial fermentation.

Regional Outlook

Based on the key geographical regions, the microbial fermentation CMO market can be segmented into four major regions, including North America, Europe, Asia-Pacific and Rest of the World. Europe is anticipated to capture the majority share of the microbial fermentation CMO market in 2024. This can be attributed to the fact that the number of manufacturing facilities in these regions is relatively higher, as compared to Asia-Pacific and players based in countries located in rest of the world region.

Microbial Fermentation CMO Market Key Players

Examples of key companies engaged in microbial fermentation CMO market (which have also been detailed profiled in this market report; the complete list of companies is available in the full report) include:

§  AGC Biologics

§  Aldevron

§  BIOVECTRA

§  Eirgenix

§  EtinPro

§  Eurogentec

§  Northway Biotech

§  Stelis Biopharma

To get market data, market insights, financial statements and a comprehensive analysis of the Microbial Fermentation CMO Market, please contact sales@rootsanalysis.com

Microbial Fermentation CMO Market Segments

Based on the research, Roots Analysis has segmented the Microbial Fermentation CMO Market into Type of Expression System, Type of Biologic, Company Size, End-user and Key Geographical Regions.

by Type of Expression System

§  Bacterial Expression System

§  Yeast Expression System

§  Other Expression Systems

by Type of Biologic

§  Recombinant Proteins

§  Enzymes

§  Plasmid DNA

§  Antibodies

§  Other Biologics

by Company Size

§  Small

§  Mid-Sized

§  Large and Very Large

by End-user

§  Pharma / Biotech Companies

§  Academic / Research Institutes

by Key Geographical Regions

§  North America

§  Europe

§  Asia-Pacific

§  Rest of the World

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